VThunter
a database for single-cell screening of virus target cells in animal kingdom
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Blue-and-yellow macaw

Scientific Name: Ara ararauna

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Sauropsida-> Sauria-> Archelosauria-> Archosauria-> Dinosauria-> Saurischia-> Theropoda-> Coelurosauria-> Aves-> Neognathae-> Psittaciformes-> Psittacidae-> Ara

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Japanese encephalitis virus

Family: Flaviviridae

Receptor: PLVAP

Receptor PLVAP information

Summary: This gene encodes a glycan-binding receptor and member of the C-type lectin family which plays a role in the immune response. C-type lectin receptors are pattern recognition receptors located on immune cells that play a role in the recognition and uptake of both self and non-self glycoproteins as well as mediating cell adhesion, glycoprotein clearance, and cell signaling functions. This gene's protein binds complex-type N-glycans of the viral envelope proteins of Ebola virus, West Nile filovirus, and SARS coronavirus, but not HIV or hepatitis C virus. In mouse, this protein has been shown to recognize activated T-cells and to negatively regulate T-cell receptor-mediated signalling. It also acts as a novel, liver-specific regulator of NK cell-mediated immunity in mouse. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2021] [NCBI]  [Proteinatlas]

Data Source

Data set information

Project Date Technology Tissue Condition Cell PMID/DOI
Vthunter_0063 2021.04 iDrop PBMC Normal 5709 Link
Featureplot of receptors

Featureplot of receptors

mRNA expression of PLVAP in human tissues   [NCBI]

Expression: Biased expression in liver (RPKM 17.2), lymph node (RPKM 6.5) and 5 other tissues

Protein expression of PLVAP in human tissues   [Proteinatlas]